Omtrent 7-9 % af den kaukasiske befolkning har variationer i CYP2D6 genet som koder for ingen- eller nedsat aktivitet af CYP2D6 (se personlig medicin ). Tramadol et produg der omdannes til den aktive metabolit through CYP2D6. Patienter med nedsat eller manglende aktivitet af CYP2D6, vil have reduceret- eller manglende effekt af tramadol.Eksperterne
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Contraindicated for individuals with extreme allergy symptoms manifested by a background of anaphylaxis, or history or presence of multiple significant allergy symptoms.Injection Depth: The product needs to be injected into the mid to deep dermis, keeping away from superficial dermis or blood vessels (consult with item Recommendations).We endorse t
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